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Ganoderma lucidum (Reishi) Mushroom Science

Reishi has been used for promoting health and longevity throughout China and Japan. Reishi has been recognised for its medicinal properties for over 2000 years with its effects documents in ancient scripts. This mushroom has a woody texture and visually looks glossy with a dark red colour. In China, this fungus is called Lingzhi while in Japan they’re named Reishi. Regardless of the names, they’re all referring to this magnificent mushroom!

Mushrooms contain a variety of bioactive molecules, such as terpenoids, steroids, phenols, glycoproteins and polysaccharides. Within the proteins found in mushrooms are proteins which contain all the essential amino acids and are especially rich in lysine and leucine. The three main bioactive constituents of reishi are polysaccharides, peptidoglycan and triterpenes. However, not all Reishi extracts are equal because of the way they are cultivated and also their environment, which is why it is important to seek quality. 

In a study by Guo-hui Wanget alin 2018, have found that patients with epilepsy who were given high doses of Reishi for 8 weeks had reduced frequency and length of seizure episodes. This is the powerful properties of reishi in calming the mind and body. Reishi’s bioactive ingredients also has an anti-ageing effect with its mechanism studied by Jue Wang and published in the journal 'Ageing and Disease'. We know that our bodily function declines as ageing occurs, this leaves us susceptible to age related disorders. The mechanism in which we age is still an area which research has no clear answers but theories which have the most interests are oxidative stress and free radical build up cause us to age. 

Beta-glucans and other polysaccharides within Reishi has an anti-oxidant effect, which inhibits the free radicals from attacking our functional cells. Not only that, the triterpenes in Reishi activates pathways within our body to recruit our immune cells and put them to work. There has been evidence suggesting that reishi is an immunomodulator with therapeutic effects such as anticancer activity, suppression of autoimmune diseases, and allergyFurther to this, the polysaccharides of reishi was studied in patients with high risks of heart diseases such as angina when given reishi powder extract. Their blood pressure decreased and most significantly was the fact that Reishi is a potent antioxidant against the pathway which leads the atherosclerosis (plaque formation in the arteries) in patients with high risk of cardiovascular disease and those with stable angina.

Reishi has many properties which benefits us holistically and can be seen that with this much research to provide evidence that supplementation is a must for anyone who is conscious about their health.



Biotonic Labs' Ganoderma Lucidum before extraction














  • Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Chapter 9 Ganoderma lucidum (Lingzhi or Reishi) Sissi Wachtel-Galor, John Yuen, John A. Buswell, and Iris F. F. Benzie. 
  • The role of polysaccharide peptide of  Ganoderma lucidumas a potent antioxidant against atherosclerosis in high risk and stable angina patients. Indian Heart Journal, 2018-09-01, Volume 70, Issue 5, Pages 608-614 
  • Wasser SP. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol. 2002;60(3):258–274.